MLB Spieler — S
1.201 MLB-Baseballspieler mit Nachnamen, die mit S beginnen.
- Saarloos, Kirk 2002–2008
- Sabathia, CC 2001–2019
- Sabel, Erik 1999–2002
- Saberhagen, Bret 1984–2001
- Sabo, Chris 1988–1996
- Sabol, Blake 2023–
- Sadecki, Ray 1960–1977
- Sadek, Mike 1973–1981
- Sadler, Casey 2014–2021
- Sadler, Donnie 1998–2007
- Sadowski, Bob 1960–1963
- Sadowski, Ed 1960–1966
- Saenz, Olmedo 1994–2007
- Saffell, Tom 1949–1955
- Sage, Harry 1890–1890
- Sager, A. J. 1994–1998
- Saggese, Thomas 2024–
- Saier, Vic 1911–1919
- Sain, Johnny 1942–1955
- Saito, Takashi 2006–2012
- Sakata, Lenn 1977–1987
- Saladino, Tyler 2015–2019
- Salas, Fernando 2010–2019
- Salas, Mark 1984–1991
- Salazar, Angel 1983–1988
- Salazar, Danny 2013–2019
- Salazar, Eduardo 2023–
- Salazar, Jeff 2006–2009
- Salazar, Lázaro
- Salazar, Luis 1980–1992
- Salazar, Oscar 2002–2010
- Sale, Chris 2010–
- Sales, Ed 1890–1890
- Salkeld, Bill 1945–1950
- Sallee, Slim 1908–1921
- Salmon, Chico 1964–1972
- Salmon, Harry
- Salmon, Tim 1992–2006
- Saltalamacchia, Jarrod 2007–2018
- Saltzgaver, Jack 1932–1945
- Salveson, Jack 1933–1945
- Salvo, Manny 1939–1943
- Samardzija, Jeff 2008–2020
- Sambito, Joe 1976–1987
- Samford, Ron 1954–1959
- Sampen, Bill 1990–1994
- Sample, Billy 1978–1986
- Sampson, Adrian 2016–2022
- Sampson, Chris 2006–2010
- Sampson, Tommy
- Samuel, Amado 1962–1964
- Samuel, Juan 1983–1998
- Sanches, Brian 2006–2012
- Sanchez, Aaron 2014–2022
- Sanchez, Adrian 2017–2021
- Sanchez, Alejandro 1982–1987
- Sanchez, Alex 2001–2005
- Sanchez, Ali 2020–
- Sanchez, Angel 2006–2013
- Sanchez, Anibal 2006–2022
- Sanchez, Carlos 2014–2022
- Sanchez, Celerino 1972–1973
- Sanchez, Cristopher 2021–
- Sanchez, Duaner 2002–2009
- Sanchez, Freddy 2002–2011
- Sanchez, Gaby 2008–2014
- Sanchez, Gary 2015–
- Sanchez, Hector 2011–2017
- Sanchez, Jesus 1998–2004
- Sanchez, Jonathan 2006–2013
- Sanchez, Luis 1981–1985
- Sanchez, Orlando 1981–1984
- Sanchez, Rey 1991–2005
- Sanchez, Tony 2013–2017
- Sand, Heinie 1923–1928
- Sandberg, Jared 2001–2003
- Sandberg, Ryne 1981–1997
- Sanders, Ben 1888–1892
- Sanders, Deion 1989–2001
- Sanders, Ken 1964–1976
- Sanders, Ray 1942–1949
- Sanders, Reggie 1991–2007
- Sanders, Scott 1993–1999
- Sanderson, Scott 1978–1996
- Sandlin, Nick 2021–
- Sandlock, Mike 1942–1953
- Sandoval, Pablo 2008–2021
- Sandoval, Patrick 2019–
- Sands, Charlie 1967–1975
- Sands, Cole 2022–
- Sands, Jerry 2011–2016
- Sanford, Fred 1943–1951
- Sanford, Jack 1956–1967
- Sanguillen, Manny 1967–1980
- Sankey, Ben 1929–1931
- Sanmartin, Reiver 2021–
- Sano, Miguel 2015–
- Sanoja, Javier 2024–
- Santa Cruz, Esteban
- Santaella, Anastasio
- Santana, Carlos 2010–
- Santana, Danny 2014–2021
- Santana, Dennis 2018–
- Santana, Domingo 2014–2020
- Santana, Edgar 2017–2021
- Santana, Ervin 2005–2021
- Santana, Johan 2000–2012
- Santana, Julio 1997–2006
- Santana, Rafael 1983–1990
- Santander, Anthony 2017–
- Santangelo, F. P. 1995–2001
- Santiago, Benito 1986–2005
- Santiago, Hector 2011–2021
- Santiago, Jose 1963–1970
- Santiago, Ramon 2002–2014
- Santillan, Tony 2021–
- Santo, Ron 1960–1974
- Santop, Louis
- Santorini, Al 1968–1973
- Santos, Gregory 2021–
- Santos, Omir 2008–2013
- Santos, Sergio 2010–2015
- Santos, Victor 2001–2007
- Santovenia, Nelson 1987–1993
- Sappelt, Dave 2011–2013
- Sardinas, Luis 2014–2018
- Sardinha, Dane 2003–2011
- Sarfate, Dennis 2006–2009
- Sargent, Joe 1921–1921
- Sarmiento, Manny 1976–1983
- Sarni, Bill 1951–1956
- Sasaki, Kazuhiro 2000–2003
- Sasser, Mackey 1987–1995
- Satin, Josh 2011–2014
- Satriano, Tom 1961–1970
- Saucedo, Tayler 2021–
- Saucier, Kevin 1978–1982
- Sauer, Ed 1943–1949
- Sauer, Hank 1941–1959
- Sauerbeck, Scott 1999–2006
- Saunders, Augustus
- Saunders, Joe 2005–2014
- Saunders, Michael 2009–2017
- Saunders, Tony 1997–1999
- Saupold, Warwick 2016–2018
- Savage, Bob 1942–1949
- Savage, Don 1944–1945
- Savage, Jimmie 1912–1915
- Savage, Ted 1962–1971
- Saverine, Bob 1959–1967
- Sawamura, Hirokazu 2021–2022
- Sawatski, Carl 1948–1963
- Sawyer, Rick 1974–1977
- Sax, Steve 1981–1994
- Say, Lou 1873–1884
- Saylor, Alfred
- Sborz, Josh 2019–
- Scahill, Rob 2012–2018
- Scala, Jerry 1948–1950
- Scales, Bobby 2009–2010
- Scales, George
- Scanlan, Bob 1991–2001
- Scanlan, Doc 1903–1911
- Scanlon, Pat 1974–1977
- Scantlebury, Patricio 1956–1956
- Scarbery, Randy 1979–1980
- Scarborough, Ray 1942–1953
- Scarce, Mac 1972–1978
- Scarritt, Russ 1929–1932
- Scarsella, Les 1935–1940
- Scarsone, Steve 1992–1999
- Schaal, Paul 1964–1974
- Schacht, Al 1919–1921
- Schaefer, Germany 1901–1918
- Schaefer, Jeff 1989–1994
- Schafer, Harry 1871–1878
- Schafer, Jordan 2009–2015
- Schafer, Logan 2011–2016
- Schaffer, Jimmie 1961–1968
- Schaffernoth, Joe 1959–1961
- Schaive, Johnny 1958–1963
- Schalk, Ray 1912–1929
- Schalk, Roy 1932–1945
- Schall, Gene 1995–1996
- Schaller, Walter 1911–1913
- Schallock, Art 1951–1955
- Schang, Bobby 1914–1927
- Schang, Wally 1913–1931
- Schanuel, Nolan 2023–
- Schanz, Charley 1944–1950
- Scharein, Art 1932–1934
- Scharein, George 1937–1940
- Schatzeder, Dan 1977–1991
- Schauer, Rube 1913–1917
- Schebler, Scott 2015–2021
- Scheer, Al 1913–1915
- Scheer, Heinie 1922–1923
- Scheffing, Bob 1941–1951
- Scheffler, Ted 1888–1890
- Scheib, Carl 1943–1954
- Scheibeck, Frank 1887–1906
- Scheinblum, Richie 1965–1974
- Schell, Danny 1954–1955
- Schenck, Bill 1882–1885
- Schenz, Hank 1946–1951
- Scheppers, Tanner 2012–2017
- Scherman, Fred 1969–1976
- Scherrer, Bill 1982–1988
- Scherzer, Max 2008–
- Schierholtz, Nate 2007–2014
- Schilling, Chuck 1961–1965
- Schilling, Curt 1988–2007
- Schimpf, Ryan 2016–2018
- Schiraldi, Calvin 1984–1991
- Schlafly, Larry 1902–1914
- Schlei, Admiral 1904–1911
- Schlereth, Daniel 2009–2012
- Schliebner, Dutch 1923–1923
- Schlitter, Brian 2010–2019
- Schlueter, Norm 1938–1944
- Schmandt, Ray 1915–1922
- Schmees, George 1952–1952
- Schmidt, Bob 1958–1965
- Schmidt, Boss 1906–1911
- Schmidt, Charles 1909–1915
- Schmidt, Clarke 2020–
- Schmidt, Dave 1981–1992
- Schmidt, Freddy 1944–1947
- Schmidt, Jason 1995–2009
- Schmidt, Mike 1972–1989
- Schmidt, Walter 1916–1925
- Schmidt, Willard 1952–1959
- Schmit, Crazy 1890–1901
- Schmitt, Casey 2023–
- Schmitz, Johnny 1941–1956
- Schneck, Dave 1972–1974
- Schneemann, Daniel 2024–
- Schneider, Brian 2000–2012
- Schneider, Dan 1963–1969
- Schneider, Davis 2023–
- Schneider, Pete 1914–1919
- Schoendienst, Red 1945–1963
- Schoeneck, Jumbo 1884–1889
- Schoeneweis, Scott 1999–2010
- Schofield, Dick 1953–1971
- Schomberg, Otto 1886–1888
- Schooler, Mike 1988–1993
- Schoonmaker, Jerry 1955–1957
- Schoop, Jonathan 2013–
- Schott, Gene 1935–1939
- Schourek, Pete 1991–2001
- Schrecongost, Ossee 1897–1908
- Schreiber, John 2019–
- Schrenk, Steve 1999–2000
- Schriver, Pop 1886–1901
- Schrock, Max 2020–2022
- Schroder, Bob 1965–1968
- Schroder, Chris 2006–2008
- Schroeder, Bill 1983–1990
- Schrom, Ken 1980–1987
- Schu, Rick 1984–1996
- Schuble, Heinie 1927–1936
- Schueler, Ron 1972–1979
- Schuemann, Max 2024–
- Schuerholz, John
- Schugel, A. J. 2015–2017
- Schulmerich, Wes 1931–1934
- Schult, Art 1953–1960
- Schulte, Frank 1904–1918
- Schulte, Fred 1927–1937
- Schulte, Ham 1940–1940
- Schulte, Johnny 1923–1932
- Schulte, Len 1944–1946
- Schultz, Barney 1955–1965
- Schultz, Bo 2014–2016
- Schultz, Bob 1951–1955
- Schultz, Buddy 1975–1979
- Schultz, Howie 1943–1948
- Schultz, Joe 1912–1925
- Schulz, Al 1912–1916
- Schulze, Don 1983–1989
- Schumacher, Hal 1931–1946
- Schumaker, Skip 2005–2015
- Schunk, Aaron 2024–
- Schupp, Ferdie 1913–1922
- Schuster, Bill 1937–1945
- Schwall, Don 1961–1967
- Schwarber, Kyle 2015–
- Schwarz, Jeff 1993–1994
- Schweitzer, Al 1908–1911
- Schwindel, Frank 2019–2022
- Scioscia, Mike 1980–1992
- Sconiers, Daryl 1981–1985
- Score, Herb 1955–1962
- Scotland, Joe
- Scott, Bob
- Scott, Donnie 1983–1991
- Scott, Ed 1900–1901
- Scott, Everett 1914–1926
- Scott, Gary 1991–1992
- Scott, George 1966–1979
- Scott, Jack 1916–1929
- Scott, Jim 1909–1917
- Scott, Joe
- Scott, John 1974–1977
- Scott, Johnie
- Scott, LeGrant 1939–1939
- Scott, Luke 2005–2013
- Scott, Mickey 1972–1977
- Scott, Mike 1979–1991
- Scott, Milt 1882–1886
- Scott, Pete 1926–1928
- Scott, Robby 2016–2019
- Scott, Rodney 1975–1982
- Scott, Tanner 2017–
- Scott, Tayler 2019–
- Scott, Tim 1991–1997
- Scott, Tony 1973–1984
- Scott, Victor 2024–
- Scribner, Evan 2011–2017
- Scrivener, Chuck 1975–1977
- Scruggs, Xavier 2014–2016
- Scudder, Scott 1989–1993
- Scurry, Rod 1980–1988
- Scutaro, Marco 2002–2014
- Seabol, Scott 2001–2005
- Seager, Corey 2015–
- Seager, Kyle 2011–2021
- Seanez, Rudy 1989–2008
- Searage, Ray 1981–1990
- Searcy, Steve 1988–1992
- Sears, JP 2022–
- Sears, Ken 1943–1946
- Seaton, Tom 1912–1917
- Seats, Tom 1940–1945
- Seaver, Tom 1967–1986
- Seay, Bobby 2001–2009
- Seay, Dick
- Sebra, Bob 1985–1990
- Sebring, Jimmy 1902–1909
- Secory, Frank 1940–1946
- See, Charlie 1919–1921
- Seeds, Bob 1930–1940
- Seelbach, Chuck 1971–1974
- Seerey, Pat 1943–1949
- Seery, Emmett 1884–1892
- Sefcik, Kevin 1995–2001
- Segedin, Rob 2016–2017
- Segui, David 1990–2004
- Segui, Diego 1962–1977
- Seguignol, Fernando 1998–2003
- Segura, Jean 2012–2023
- Seibold, Socks 1915–1933
- Seitzer, Kevin 1986–1997
- Selbach, Kip 1894–1906
- Selby, Bill 1996–2003
- Sele, Aaron 1993–2007
- Selee, Frank
- Selig, Bud
- Selkirk, George 1934–1942
- Sellers, Jeff 1985–1988
- Sellers, Justin 2011–2014
- Sells, Dave 1972–1975
- Selma, Dick 1965–1974
- Selman, Sam 2019–2022
- Selph, Carey 1929–1932
- Sembera, Carroll 1965–1970
- Semien, Marcus 2013–
- Seminick, Andy 1943–1957
- Semproch, Ray 1958–1961
- Senga, Kodai 2023–
- Sensenderfer, Count 1871–1874
- Sentell, Paul 1906–1907
- Senzatela, Antonio 2017–
- Senzel, Nick 2019–
- Seo, Jae Weong 2002–2007
- Serad, Billy 1884–1888
- Serafini, Dan 1996–2007
- Serena, Bill 1949–1954
- Serna, Paul 1981–1982
- Serrell, Bonnie
- Serum, Gary 1977–1979
- Servais, Scott 1991–2001
- Serven, Brian 2022–
- Service, Scott 1988–2004
- Severeid, Hank 1911–1926
- Severino, Luis 2015–
- Severino, Pedro 2015–2022
- Severinsen, Al 1969–1972
- Severson, Rich 1970–1971
- Sewald, Paul 2017–
- Seward, Ed 1885–1891
- Seward, George 1875–1882
- Sewell, Joe 1920–1933
- Sewell, Luke 1921–1942
- Sewell, Rip 1932–1949
- Sexson, Richie 1997–2008
- Sexton, Chris 1999–2000
- Sexton, Jimmy 1977–1983
- Seybold, Socks 1899–1908
- Seymour, Cy 1896–1913
- Shackelford, Brian 2005–2006
- Shackelford, John
- Shafer, Orator 1874–1890
- Shafer, Taylor 1884–1890
- Shafer, Tillie 1909–1913
- Shaffer, Richie 2015–2016
- Shamsky, Art 1965–1972
- Shaner, Wally 1923–1929
- Shanks, Howie 1912–1925
- Shannon, Dan 1889–1891
- Shannon, Mike 1962–1970
- Shannon, Red 1915–1926
- Shannon, Spike 1904–1908
- Shannon, Wally 1959–1960
- Shantz, Billy 1954–1960
- Shantz, Bobby 1949–1964
- Sharon, Dick 1973–1975
- Sharp, Bill 1973–1976
- Sharpe, Bud 1905–1910
- Sharperson, Mike 1987–1995
- Sharrott, Jack 1890–1893
- Shaute, Joe 1922–1934
- Shave, Jon 1993–1999
- Shaw, Al 1901–1909
- Shaw, Bob 1957–1967
- Shaw, Bryan 2011–
- Shaw, Don 1967–1972
- Shaw, Dupee 1883–1888
- Shaw, Jeff 1990–2001
- Shaw, Jim 1913–1921
- Shaw, Matt 2025–
- Shaw, Ted
- Shaw, Travis 2015–2022
- Shawkey, Bob 1913–1927
- Shay, Danny 1901–1907
- Shea, Merv 1927–1944
- Shea, Spec 1947–1955
- Sheaffer, Danny 1987–1997
- Shealy, Ryan 2005–2010
- Shean, Dave 1906–1919
- Sheckard, Jimmy 1897–1913
- Sheehan, Timothy 1895–1896
- Sheehan, Tom 1915–1926
- Sheehan, Tommy 1900–1908
- Sheely, Bud 1951–1953
- Sheely, Earl 1921–1931
- Sheets, Andy 1996–2002
- Sheets, Ben 2001–2012
- Sheets, Gavin 2021–
- Sheets, Larry 1984–1993
- Sheffield, Gary 1988–2009
- Shelby, John 1981–1991
- Sheldon, Bob 1974–1977
- Sheldon, Rollie 1961–1966
- Sheldon, Scott 1997–2001
- Shellenback, Jim 1966–1977
- Shelton, Chris 2004–2009
- Shepard, Jack 1953–1956
- Shepherd, Ron 1984–1986
- Sheppard, Ray
- Sherdel, Bill 1918–1932
- Sherfy, James 2017–2021
- Sherid, Roy 1929–1931
- Sheridan, Pat 1981–1991
- Sherlock, John 1930–1930
- Sherrill, George 2004–2012
- Sherry, Larry 1958–1968
- Sherry, Norm 1959–1963
- Shetrone, Barry 1959–1963
- Shetzline, John 1882–1882
- Shevlin, Jimmy 1930–1934
- Shields, James 2006–2018
- Shields, Scot 2001–2010
- Shields, Steve 1985–1989
- Shindle, Billy 1886–1898
- Shines, Razor 1983–1987
- Shinjo, Tsuyoshi 2001–2003
- Shinners, Ralph 1922–1925
- Shinnick, Tim 1890–1891
- Shipke, Bill 1906–1909
- Shipley, Craig 1986–1998
- Shires, Art 1928–1932
- Shirley, Bart 1964–1968
- Shirley, Bob 1977–1987
- Shirley, Tex 1941–1946
- Shively, George
- Shoch, George 1886–1897
- Shocker, Urban 1916–1928
- Shockley, Costen 1964–1965
- Shoemaker, Matt 2013–2021
- Shoffner, Milt 1929–1940
- Shopay, Tom 1967–1977
- Shoppach, Kelly 2005–2013
- Shore, Ernie 1912–1920
- Shores, Bill 1928–1936
- Short, Bill 1960–1969
- Short, Chris 1959–1973
- Short, Zack 2021–
- Shorten, Chick 1915–1924
- Shotton, Burt 1909–1923
- Shoun, Clyde 1935–1949
- Shouse, Brian 1993–2009
- Show, Eric 1981–1991
- Shreve, Chasen 2014–
- Shreve, Lev 1887–1889
- Shuba, George 1948–1955
- Shuck, JB 2011–2019
- Shuey, Paul 1994–2007
- Shugart, Frank 1890–1901
- Shumpert, Terry 1990–2003
- Shupe, Vince 1945–1945
- Shuster, Jared 2023–
- Siani, Michael 2022–
- Sicking, Ed 1916–1927
- Siddall, Joe 1993–1998
- Siebern, Norm 1956–1968
- Siebert, Dick 1932–1945
- Siebert, Paul 1974–1978
- Siebert, Sonny 1964–1975
- Siegrist, Kevin 2013–2017
- Sierra, Felipe
- Sierra, Magneuris 2017–2022
- Sierra, Moises 2012–2018
- Sierra, Ruben 1986–2006
- Siever, Ed 1901–1908
- Sievers, Roy 1949–1965
- Sigafoos, Frank 1926–1931
- Sigman, Tripp 1929–1930
- Silva, Carlos 2002–2010
- Silva, Jose 1996–2002
- Silvera, Charlie 1948–1957
- Silvestri, Dave 1992–1999
- Silvestri, Ken 1939–1951
- Sima, Al 1950–1954
- Simas, Bill 1995–2000
- Simmons, Al 1924–1944
- Simmons, Andrelton 2012–2022
- Simmons, Brian 1998–2001
- Simmons, Curt 1947–1967
- Simmons, Hack 1910–1915
- Simmons, Joe 1871–1875
- Simmons, John 1949–1949
- Simmons, Nelson 1984–1987
- Simmons, Ted 1968–1988
- Simms, Mike 1990–1999
- Simms, Willie
- Simon, Alfredo 2008–2016
- Simon, Hank 1887–1890
- Simon, Mike 1909–1915
- Simon, Randall 1997–2006
- Simons, Mel 1931–1932
- Simontacchi, Jason 2002–2007
- Simpson, Chandler 2025–
- Simpson, Dick 1962–1969
- Simpson, Harry 1951–1959
- Simpson, Joe 1975–1983
- Simpson, Wayne 1970–1977
- Sims, Duke 1964–1974
- Sims, Lucas 2017–
- Sinatro, Matt 1981–1992
- Singer, Bill 1964–1977
- Singer, Brady 2020–
- Singer, Orville
- Singleton, Chris 1999–2005
- Singleton, Elmer 1945–1959
- Singleton, Jon 2014–
- Singleton, Ken 1970–1984
- Sington, Fred 1934–1939
- Sipek, Dick 1945–1945
- Sipin, John 1969–1969
- Sipp, Tony 2009–2019
- Siri, Jose 2021–
- Sirotka, Mike 1995–2000
- Sisco, Andy 2005–2007
- Sisco, Chance 2017–2021
- Sisk, Doug 1982–1991
- Sisk, Tommie 1962–1970
- Sisler, Dave 1956–1962
- Sisler, Dick 1946–1953
- Sisler, George 1915–1930
- Sisti, Sibby 1939–1954
- Sivess, Pete 1936–1938
- Sizemore, Grady 2004–2015
- Sizemore, Scott 2010–2014
- Sizemore, Ted 1969–1980
- Skaggs, Dave 1977–1980
- Skaggs, Tyler 2012–2019
- Skenes, Paul 2024–
- Skinner, Bob 1954–1966
- Skinner, Joel 1983–1991
- Skizas, Lou 1956–1959
- Skok, Craig 1973–1979
- Skowron, Bill 1954–1967
- Skubal, Tarik 2020–
- Slade, Gordon 1930–1935
- Slagle, Jimmy 1899–1908
- Slaten, Doug 2006–2012
- Slaten, Justin 2024–
- Slater, Austin 2017–
- Slaton, Jim 1971–1986
- Slattery, Jack 1901–1909
- Slattery, Mike 1884–1891
- Slaught, Don 1982–1997
- Slaughter, Enos 1938–1959
- Sleater, Lou 1950–1958
- Sledge, Terrmel 2004–2007
- Sloan, Bruce 1944–1944
- Sloan, Tod 1913–1919
- Slocum, Ron 1969–1971
- Slocumb, Heathcliff 1991–2000
- Slowey, Kevin 2007–2014
- Slusarski, Joe 1991–2001
- Small, Aaron 1994–2006
- Small, Jim 1955–1958
- Smalley, Roy 1948–1958
- Smalley, Will 1890–1891
- Smiley, Bill 1874–1882
- Smiley, John 1986–1997
- Smith, Al 1934–1945
- Smith, Aleck 1897–1906
- Smith, Bernie 1970–1971
- Smith, Big Bill
- Smith, Billy 1975–1981
- Smith, Bob 1923–1937
- Smith, Bobby 1957–1965
- Smith, Bryn 1981–1993
- Smith, Bud 2001–2002
- Smith, Burch 2013–
- Smith, Cade 2024–
- Smith, Caleb 2017–2022
- Smith, Cam 2025–
- Smith, Carson 2014–2018
- Smith, Charley 1960–1969
- Smith, Charlie 1902–1914
- Smith, Chris 2008–2017
- Smith, Clarence
- Smith, Cleo
- Smith, Dan 1999–2003
- Smith, Dave 1980–1992
- Smith, Dick 1951–1955
- Smith, Dominic 2017–
- Smith, Drew 2018–
- Smith, Dwight 1989–1996
- Smith, Earl 1916–1922
- Smith, Eddie 1936–1947
- Smith, Elmer 1886–1901
- Smith, Ernie
- Smith, Eugene
- Smith, Ford
- Smith, Frank 1904–1915
- Smith, Fred 1913–1917
- Smith, George 1916–1923
- Smith, Germany 1884–1898
- Smith, Hal 1932–1935
- Smith, Harry 1901–1910
- Smith, Henry
- Smith, Hilton
- Smith, Jack 1915–1929
- Smith, Jason 2001–2009
- Smith, Jimmy 1914–1922
- Smith, Joe 2007–2022
- Smith, John 1882–1882
- Smith, Johnny
- Smith, Jordan 2010–2011
- Smith, Josh 2015–2020
- Smith, Jud 1893–1901
- Smith, Keith 1977–1980
- Smith, Ken 1981–1983
- Smith, Kevan 2016–2021
- Smith, Kevin 2021–
- Smith, Lee 1980–1997
- Smith, Lonnie 1978–1994
- Smith, Mallex 2016–2020
- Smith, Mark 1994–2003
- Smith, Mayo 1945–1945
- Smith, Ozzie 1978–1996
- Smith, Paul 1953–1958
- Smith, Pavin 2020–
- Smith, Pete 1987–1998
- Smith, Phenomenal 1884–1891
- Smith, Pop 1880–1891
- Smith, Ray 1981–1983
- Smith, Red 1911–1919
- Smith, Reggie 1966–1982
- Smith, Roy 1984–1991
- Smith, Seth 2007–2017
- Smith, Sherry 1911–1927
- Smith, Skyrocket 1888–1888
- Smith, Syd 1908–1915
- Smith, Theolic
- Smith, Tommy 1973–1977
- Smith, Tony 1907–1911
- Smith, Wally 1911–1914
- Smith, Will 2012–
- Smith, Willie 1963–1971
- Smith, Wyman
- Smith, Zane 1984–1996
- Smithson, Mike 1982–1989
- Smoak, Justin 2010–2020
- Smoker, Josh 2016–2018
- Smolinski, Jake 2014–2018
- Smoltz, John 1988–2009
- Smoot, Homer 1902–1906
- Smyly, Drew 2012–
- Smyth, Red 1915–1918
- Smythe, Harry 1929–1934
- Snead, Kirby 2021–
- Snead, Sylvester
- Sneed, John 1884–1891
- Snell, Blake 2016–
- Snell, Ian 2004–2010
- Snell, Nate 1984–1987
- Snelling, Chris 2002–2008
- Snider, Collin 2022–
- Snider, Duke 1947–1964
- Snider, Travis 2008–2015
- Snodgrass, Fred 1908–1916
- Snopek, Chris 1995–1998
- Snow, Felton
- Snow, J. T. 1992–2008
- Snyder, Brandon 2010–2018
- Snyder, Chris 2004–2013
- Snyder, Cory 1986–1994
- Snyder, Emanuel 1876–1884
- Snyder, Frank 1912–1927
- Snyder, Jerry 1952–1958
- Snyder, John 1998–2000
- Snyder, Kyle 2003–2008
- Snyder, Pop 1873–1891
- Snyder, Russ 1959–1970
- Sobotka, Chad 2018–2020
- Sockalexis, Chief 1897–1899
- Socolovich, Miguel 2012–2018
- Soderholm, Eric 1971–1980
- Soderstrom, Tyler 2023–
- Sodowsky, Clint 1995–1999
- Sofield, Rick 1979–1981
- Sogard, Eric 2010–2021
- Sogard, Nick 2024–
- Sojo, Luis 1990–2003
- Solaita, Tony 1968–1979
- Solak, Nick 2019–
- Solano, Donovan 2012–
- Solano, Julio 1983–1989
- Solarte, Yangervis 2014–2019
- Soler, Jorge 2014–
- Solis, Sammy 2015–2018
- Solís, Miguel
- Solomon, Eddie 1973–1982
- Solters, Moose 1934–1943
- Somerville, Ed 1875–1876
- Sommer, Joe 1880–1890
- Sommers, Andy 1887–1890
- Sommers, Bill 1950–1950
- Songer, Don 1924–1927
- Sonnanstine, Andy 2007–2011
- Sorensen, Lary 1977–1988
- Soria, Joakim 2007–2021
- Soriano, Alfonso 1999–2014
- Soriano, George 2023–
- Soriano, José 2023–
- Soriano, Rafael 2002–2015
- Soroka, Mike 2018–
- Sorrell, Billy 1965–1970
- Sorrell, Vic 1928–1937
- Sorrento, Paul 1989–1999
- Sosa, Edmundo 2018–
- Sosa, Elias 1972–1983
- Sosa, Jorge 2002–2010
- Sosa, Lenyn 2022–
- Sosa, Sammy 1989–2007
- Sothern, Denny 1926–1931
- Sothoron, Allen 1914–1926
- Soto, Geovany 2005–2017
- Soto, Gregory 2019–
- Soto, Juan 2018–
- Soto, Mario 1977–1988
- Souchock, Bud 1946–1955
- Souell, Herb
- Sousa, Bennett 2022–
- Southworth, Billy 1913–1929
- Souza, Steven 2014–2022
- Sowders, Bill 1888–1890
- Sowders, John 1887–1890
- Sowers, Jeremy 2006–2009
- Spade, Bob 1907–1910
- Spahn, Warren 1942–1965
- Spalding, Al 1871–1878
- Spalding, Dick 1927–1928
- Span, Denard 2008–2018
- Spangenberg, Cory 2014–2022
- Spangler, Al 1959–1971
- Sparkman, Glenn 2017–2020
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